Synthesis of Novel 2-(Methylthio)benzo[g][1,2,4]triazolo[1,5-a]quinazolin- 5-(4H)-one and its Derivatives

Author(s): Rashad A. Al-Salahi, Mohamed S. Marzouk, Hazem A. Ghabbour, Fun H. Kun

Journal Name: Letters in Organic Chemistry

Volume 11 , Issue 10 , 2014

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Graphical Abstract:


A novel 2-(methylthio)benzo[g][1,2,4]triazolo[1,5-a]quinazolin-5(4H)-one was synthesized employing dimethyl N-cyanoimidodithiocarbonate and 3-hydrazinyl-2-naphthoic acid as building blocks. Chemical transformation of the inherent lactam group in the target molecule provided access to a variety of heterocylic derivatives. The obtained compounds are characterized and confirmed by NMR, IR, and HREI-MS analyses.

Keywords: 3-hydrazinyl-2-naphthoic acid, cyclocondensation, dimethyl N-cyanoimidodithiocarbonate.

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Article Details

Year: 2014
Published on: 13 August, 2014
Page: [759 - 767]
Pages: 9
DOI: 10.2174/1570178611666140813205111
Price: $65

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