LEPROSY Chasing Potential Antileprotic Compounds
Pp. 122-148 (27)
Dênis Pires de Lima and Davidson Pires de Lima
Leprosy is still considered one of the world’s important chronic diseases.
Although multidrug therapy (MDT) has contributed to decline of its incidence, there are
still hundreds of thousands of new cases each year. A full understanding of the
physiological, clinical, transmission, immunology, genetic and bacterial aspects of this
disease is very important to track the problem by multidisciplinary scientific
investigation. Excellent work on the design and synthesis of new drugs to treat Leprosy
is being performed all over the world, and is included in this manuscript. Nevertheless,
studies to find more effective drugs to treat leprosy are still needed. Leprosy and others
parasitic, bacterial, viral and protozoan infections form the group of neglected tropical
diseases (NTD) and are among the leading causes of chronic disability and poverty in
low- and middle-income countries.
Antileprotic, leprosy, synthetic studies.
Federal University of Mato Grosso do Sul, Institute of Chemistry, 79070-900, Campo Grande, MS, Brazil.