Abstract
This review focuses on principles of product preservation, preservatives, and novel technologies for the future development of preservative free herbal products. The purpose of this study was to determine the amount of preservatives in pharmaceutical products as some recent studies reported serious side effects associated with the ingestion of these substances. The principles involved were asepsis and removal of microorganisms — both static and cidal effects. Some of the novel technologies of asepsis are high pressure processing, pulsed electric field treatment and non-thermal technologies including ultraviolet processing. All relevant literature databases were searched upto 2011. Majority of the human, animal, in vitro studies, and reviews were included. Preservative free dosage forms must be formulated for the reduction in side effects and hence a healthier mankind.
Keywords: High pressure shift freezing, osmotic filtration, parabens, pasteurization, pulsed electric technique.
The Natural Products Journal
Title:Design and Development of Preservative Free Herbal Dosage Forms
Volume: 4 Issue: 1
Author(s): H.B. Pushpalatha, T.M. Pramod Kumar, U. Aravind Padiyar and Sundaram
Affiliation:
Keywords: High pressure shift freezing, osmotic filtration, parabens, pasteurization, pulsed electric technique.
Abstract: This review focuses on principles of product preservation, preservatives, and novel technologies for the future development of preservative free herbal products. The purpose of this study was to determine the amount of preservatives in pharmaceutical products as some recent studies reported serious side effects associated with the ingestion of these substances. The principles involved were asepsis and removal of microorganisms — both static and cidal effects. Some of the novel technologies of asepsis are high pressure processing, pulsed electric field treatment and non-thermal technologies including ultraviolet processing. All relevant literature databases were searched upto 2011. Majority of the human, animal, in vitro studies, and reviews were included. Preservative free dosage forms must be formulated for the reduction in side effects and hence a healthier mankind.
Export Options
About this article
Cite this article as:
Pushpalatha H.B., Kumar T.M. Pramod, Padiyar U. Aravind and Sundaram , Design and Development of Preservative Free Herbal Dosage Forms, The Natural Products Journal 2014; 4 (1) . https://dx.doi.org/10.2174/221031550401140715151438
DOI https://dx.doi.org/10.2174/221031550401140715151438 |
Print ISSN 2210-3155 |
Publisher Name Bentham Science Publisher |
Online ISSN 2210-3163 |
Call for Papers in Thematic Issues
Ayurvedic medicinal therapeutic approaches for inflammatory and neurodegenerative disorders
Usually, in our elderly population, neurodegenerative disorders occur due to neuron death. Alzheimer?s disease (AD) is an irreversible and progressive neurodegenerative disease. Dementia is the leading cause of AD, which affects about 30 million people worldwide. According to the World Alzheimer report 2018, a new case of dementia develops every ...read more
Recent Advances in Biotransformation of Bioactive Terpenoids using Aspergillus niger
Biotransformation is the reaction catalyzed by biological catalysts of either isolated enzymes or whole cell cultures of microorganisms. This process has been extensively applied in the conversion of bioactive terpenoids with high regio- and stereospecifity. This process has been also applied in the lead discovery and development. Aspergillus niger has ...read more
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Intravenous Immunoglobulin Therapy in Dermatologic Disorders
Inflammation & Allergy - Drug Targets (Discontinued) The Role of Immunosuppressive Medications in the Pathogenesis of Hypertension and Efficacy and Safety of Antihypertensive Agents in Kidney Transplant Recipients
Current Medicinal Chemistry Immunotherapy for Food Allergies in Children
Current Pharmaceutical Design Occupational Allergy in Healthcare Workers
Recent Patents on Inflammation & Allergy Drug Discovery Nummular Eczema: An Updated Review
Recent Patents on Inflammation & Allergy Drug Discovery 3D QSAR Studies on Substituted Benzimidazole Derivatives as Angiotensin II-AT<sub>1</sub> Receptor Antagonist
Current Computer-Aided Drug Design Drugs in Pediatric Ischemic Stroke
Current Drug Targets Chemistry and Pharmacology of Angiotensin-Converting Enzyme Inhibitors
Current Pharmaceutical Design A Systematic Approach to Assess the Burden of Drug Interactions in Adult Kidney Transplant Patients
Current Drug Safety Adverse Effects of Antihistamines on Skin Tests and Antihistamines in Pregnancy
Current Medicinal Chemistry - Anti-Inflammatory & Anti-Allergy Agents Editorial [Hot Topic: An Update on the Diagnosis of Allergic and Non-Allergic Drug Hypersensitivity (Executive Editors: M.T. Ventura and A. Romano) ]
Current Pharmaceutical Design Occupational Respiratory Pathology in Russia: Current Trends and Challenges
Current Respiratory Medicine Reviews Desensitization Protocol for Rituximab-Induced Serum Sickness
Current Drug Safety Parvalbumin as a Pleomorphic Protein
Current Protein & Peptide Science New Strategies and Drugs in the Treatment of Hypertension: Monotherapy or Combination?
Recent Patents on Cardiovascular Drug Discovery Meet the Editorial Board Member
Recent Patents on Inflammation & Allergy Drug Discovery Pharmacological, Immunological, and Gene Targeting of the Renin-Angiotensin System for Treatment of Cardiovascular Disease
Current Pharmaceutical Design Insulin Therapy for Diabetes Epidemic: A Patent Review
Current Drug Delivery Allergic and Pseudoallergic Reactions Induced by Glucocorticoids: A Review
Current Pharmaceutical Design Adamantane – A Lead Structure for Drugs in Clinical Practice
Current Medicinal Chemistry