This study documents that mumps virus shares several peptide sequences with human proteins that, when
altered, may be involved in oligospermia/azoospermia, sterility and testicular atrophy. Examples are sperm flagellar protein 2
and spermatogenesis and centriole-associated protein 1. The data invite to further investigate crossreactivity as a potential
mechanism linking anti-mumps immune responses, alterations of spermatogenesis–associated antigens and male fertility
Keywords: Infertility, mumps immunogenicity, peptide crossreactivity, spermatogenesis-associated proteins, sterility.
Rights & PermissionsPrintExport