Plant Derived Edible Vaccines and Therapeutics
Pp. 200-236 (37)
Emrah Altindis, Sultan Gulce Iz, Mehmet Ozgun Ozen, Pinar Nartop, Ismet Deliloglu Gurhan and Aynur Gurel
Defining the molecular basis of the infectious diseases by the highly
accumulated data on genetics and molecular biology facilitated developing new
prophylactic and therapeutic vaccination strategies against human and animal diseases.
On the other hand, vaccine development process still has many technical and
economical limitations. Therefore, low-income countries, which do not have powerful
healthcare infrastructure, neither produce their own vaccines nor benefit enough from
the current vaccination programs. In this aspect, plants are promising to be used as
biofactories for producing edible vaccines and several therapeutics due to their easy
manipulations and also low-cost manufacturing properties. In this chapter, the
advantages, limitations of the edible vaccines, the studies related to plant-derived edible
vaccines and therapeutics up to date are summarized.
Plant derived edible vaccines, therapeutics, recombinant proteins.
Harvard Medical School, Microbiology and Immunobiology Department, Room 1039, 77 Avenue Louis Pasteur Boston, MA 02115, USA