Synthesis of Allosamidin and its Analogues

Author(s): Gangliang Huang, Qilin Tang

Journal Name: Current Organic Synthesis

Volume 11 , Issue 5 , 2014

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Graphical Abstract:


The pseudo-trisaccharide allosamidin 1 is a potent inhibitor of all family 18 chitinases, and it is confirmed to have biological activities against insects and fungi. The solid/liquid phase syntheses of allosamidin 1 and its analogues have been developed in recent years, and these compounds can be obtained by iterative glycosylation reactions, catalytic hydrogenation, acetylation, deacetylation, or photolysis, respectively.

Keywords: Allosamidin, analogues, recent development, synthesis.

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Article Details

Year: 2014
Page: [696 - 700]
Pages: 5
DOI: 10.2174/1570179411666140623223120
Price: $65

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PDF: 15