The synthesis of a new non-cross-linked polystyrene supported cyclosulfamide chiral auxiliary is described.
Asymmetric aldol reactions using this auxiliary proceeded with good yields and excellent stereoselectivities, which were
comparable with those observed by using non-supported cyclosulfamide chiral auxiliary. Furthermore, recovery and recycling
of this polymer supported chiral auxiliary have been successfully achieved without appreciable reduction in the
yield or stereoselectivity.
Keywords: Asymmetric aldol reactions, chiral auxiliary, cyclosulfamide, non-cross-linked polystyrene, supported.
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