Glycosylation Employing Unprotected Carbohydrate Acceptor Components

Author(s): Stephan Bottcher, Joachim Thiem

Journal Name: Current Organic Chemistry

Volume 18 , Issue 14 , 2014

Become EABM
Become Reviewer
Call for Editor


This review discusses concepts towards facile non-enzymatic glycosylation of unprotected or lightly protected glycostructures. These comprise approaches in which reactivity distinction of hydroxyl groups is achieved via stannylene or boronic and borinic acid intermediates as well as via oxyanion formation along with syntheses based on selectivity implemented by the substrates themselves. Further, syntheses of complex glycostructures and oligosaccharides are shown, as well as the concept of random glycosylation towards glycoside libraries with desired equal product distribution.

Keywords: Base promoted, boronic/borinic acid mediated, glycosylation, random approach, stannylene-mediated, substance controlled, unprotected/partially protected acceptors.

Rights & PermissionsPrintExport Cite as

Article Details

Year: 2014
Published on: 04 September, 2014
Page: [1804 - 1817]
Pages: 14
DOI: 10.2174/1385272819666140527231701
Price: $58

Article Metrics

PDF: 24