Optical Coherence Tomography: A Journey from Clinical Research to Daily Interventional Practice

Author(s): Gioel G. Secco, Matteo Ghione, Gianni Dall’Ara, Rosario Parisi, Alessio Mattesini, Rossella Fattori, Andrea Rognoni, Giuseppe De Luca, Giulia Genoni, Paolo N. Marino, Carlo Di Mario

Journal Name: Recent Patents on Medical Imaging (Discontinued)

Volume 4 , Issue 1 , 2014


Angiography has been the cornerstone tool to assess coronary anatomy, leading to a rapid development of percutaneous revascularization techniques. Despite the widespread dissemination and high reproducibility, angiography alone can only provide a limited analysis of the lumen profile, without the possibility to disclose vessel wall characteristics and the composition of coronary lesions. Intracoronary imaging techniques have been developed to overcome these limitations. Intravascular ultrasound (IVUS) was the first intracoronary imaging modality introduced two decades before, followed more than a decade after by optical coherence tomography (OCT), a light based technology. This article presents the current status in the technical background of OCT imaging in the areas of research development and clinical practice, focusing on future developments of related patent forms.

Keywords: Coronary arteries, coronary atherosclerosis, coronary plaque, optical coherence tomography, thin-cap fibroatheroma.

promotion: free to download

Rights & PermissionsPrintExport Cite as

Article Details

Year: 2014
Page: [16 - 21]
Pages: 6
DOI: 10.2174/2210684704666140526230749

Article Metrics

PDF: 26