Synthesis, characterization and investigation of antimicrobial activities of ten novel tetrahydroindazolylthiazoles
is presented. Their structures were determined using 1H and 13C NMR, FAB(+)-MS and HRMS analyses.
Among the derivatives, compound 3f shows strong antibacterial activity against S. aureus ATCC 43300, S. aureus ATCC
25923, and S. epidermidis ATCC 12228 with MIC 7.81 µg/ml, and good activity against S. aureus ATCC 6538 with MIC
31.25 µg/ml. Compounds 3a-e and 3j show good antifungal activity with MIC values ranging from 31.25 µg/ml to 250