Amniotic fluid embolism (AFE) is a rare and severe obstetric emergency and a significant cause of maternal
mortality in developed countries and its incidence varies according to different studies. Presently, advances in the understanding
of this pathology continue to be slowed down for the absence of generally accepted diagnostic criteria, the clinical
analogies of this entity to other types of acute dangerous maternal illnesses and the presence of a wide range of disease
severity. The aim of this review has been to evaluate the incidence of AFE, the role of possible risk factors, the clinical
presentation (signs and symptoms) and outcome. Secondly the authors reviewed the management of these very difficult
patients, including treatments and interventions in order to extrapolate sharable recommendations for the management of
these complicated patients.
Keywords: Amniotic fluid embolism, incidence, risk factors, management and treatment, scientific evidence.
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