The pharmaceutical industry heavily relies on external sources to supplement its internal R&D activities and
fill its product pipelines. Outsourcing of workpackages, in-licensing of development projects, collaborations with
academic research centers or biotech companies and hiring of consultants are classic approaches towards this goal. Here
we describe a new open innovation approach, termed “fluctuating open teams (FLOT)” that combines synergistically
internal and external talent for a drug discovery project. The approach is compared to other open innovation options and
constitutes an ideal way to boost creativity and new ideas for project teams that hit a roadblock.
Keywords: Creativity, crowd sourcing, diversity, drug discovery, open innovation, project teams, research and development.
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