[1, 2, 4]-Oxadiazoles: Synthesis and Biological Applications

Author(s): Rajesh O. Bora, Bashir Dar, Vidya Pradhan, Mazahar Farooqui

Journal Name: Mini-Reviews in Medicinal Chemistry

Volume 14 , Issue 4 , 2014

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In the present article synthesis and medicinal applications of [1, 2, 4] oxadiazoles are reviewed. The oxadiazoles have a wide range of applications such as Antitussive, Anti-inflammatory, Anaesthetic, Vasodilator, anthelmintic, antiallergic, antiplatelet effects in vitro, antithrombotic properties in vivo, etc. Many researchers have synthesized novel heterocyclic compounds containing oxadiazoles with the concept of bioisosterism.

Keywords: Anaesthetic angent, anti-inflammatory, anti-tumor agents, heterocycles, one pot synthesis, [1, 2, 4] oxadiazoles, synthetic methods.

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Article Details

Year: 2014
Published on: 07 April, 2014
Page: [355 - 369]
Pages: 15
DOI: 10.2174/1389557514666140329200745
Price: $65

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