Abstract
Phytochemistry accords with phytochemicals which are obtained from a plant source. In recent years, there is a great insistence to phytochemical constituents as they are devoid of adverse reactions. On account of lack of modern scientific evidence for their basis of action on diseases, a crude extract is not well accepted. But due to the adverse side effects & increasing failure of modern drugs to cure the ailments, the attention has been turned back towards ancient systems of medicine, such as, Ayurveda, Unani and Chinese. Consequently, plants have once again attained the centre stage in the efforts aimed at developing effective drugs for diseases incurable by modern medicine system. Hence, the present issue was aimed to point out the in detail study of the phytochemical compounds including but not limited to isolation, structure elucidation, in silico studies(molecular docking, QSAR etc) and assessment of therapeutic potential which would aid in understanding the chemical structures better as therapeutic agent.
Keywords: Phytochemistry, in silico studies, QSAR, drug likeness, bioactives.
Current Topics in Medicinal Chemistry
Title:Editorial (Thematic Issue: From Phytochemistry to Medicinal Chemistry: Isolation, Semisynthesis, Evaluation and Computational Studies)
Volume: 14 Issue: 8
Author(s): Rajeev K. Singla, G. Varadaraj Bhat and Humberto Gonzalez-Diaz
Affiliation:
Keywords: Phytochemistry, in silico studies, QSAR, drug likeness, bioactives.
Abstract: Phytochemistry accords with phytochemicals which are obtained from a plant source. In recent years, there is a great insistence to phytochemical constituents as they are devoid of adverse reactions. On account of lack of modern scientific evidence for their basis of action on diseases, a crude extract is not well accepted. But due to the adverse side effects & increasing failure of modern drugs to cure the ailments, the attention has been turned back towards ancient systems of medicine, such as, Ayurveda, Unani and Chinese. Consequently, plants have once again attained the centre stage in the efforts aimed at developing effective drugs for diseases incurable by modern medicine system. Hence, the present issue was aimed to point out the in detail study of the phytochemical compounds including but not limited to isolation, structure elucidation, in silico studies(molecular docking, QSAR etc) and assessment of therapeutic potential which would aid in understanding the chemical structures better as therapeutic agent.
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Cite this article as:
Singla K. Rajeev, Bhat Varadaraj G. and Gonzalez-Diaz Humberto, Editorial (Thematic Issue: From Phytochemistry to Medicinal Chemistry: Isolation, Semisynthesis, Evaluation and Computational Studies), Current Topics in Medicinal Chemistry 2014; 14 (8) . https://dx.doi.org/10.2174/1568026614666140324145723
DOI https://dx.doi.org/10.2174/1568026614666140324145723 |
Print ISSN 1568-0266 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-4294 |
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