Abstract
The discovery and exploitation of new drug targets is a key focus for both the pharmaceutical industry and academic research. To provide an insight into trends in the exploitation of new drug targets, we have analysed different methods during the past six decades and advances made in drug target discovery. A special focus remains on different methods used for drug target discovery on infectious diseases such as Tuberculosis, Gastritis, Malaria, Trypanosomiasis and Leishmaniasis. We herewith provide a paradigm that is can be used for drug target discovery in the near future.
Keywords: Drug targets, Helicobacter pylori, infectious diseases, Leishmania, Mycobacterium tuberculosis, new paradigm, Plasmodium falciparum, Trypanosoma.
Infectious Disorders - Drug Targets
Title:New Strategies and Paradigm for Drug Target Discovery: A Special Focus on Infectious Diseases Tuberculosis, Malaria, Leishmaniasis, Trypanosomiasis and Gastritis
Volume: 13 Issue: 5
Author(s): Nageswara R.R. Neelapu, Ravi C.P.K. Srimath-Tirumala-Peddinti, Deepthi Nammi and Amita C.M. Pasupuleti
Affiliation:
Keywords: Drug targets, Helicobacter pylori, infectious diseases, Leishmania, Mycobacterium tuberculosis, new paradigm, Plasmodium falciparum, Trypanosoma.
Abstract: The discovery and exploitation of new drug targets is a key focus for both the pharmaceutical industry and academic research. To provide an insight into trends in the exploitation of new drug targets, we have analysed different methods during the past six decades and advances made in drug target discovery. A special focus remains on different methods used for drug target discovery on infectious diseases such as Tuberculosis, Gastritis, Malaria, Trypanosomiasis and Leishmaniasis. We herewith provide a paradigm that is can be used for drug target discovery in the near future.
Export Options
About this article
Cite this article as:
Neelapu R.R. Nageswara, Srimath-Tirumala-Peddinti C.P.K. Ravi, Nammi Deepthi and Pasupuleti C.M. Amita, New Strategies and Paradigm for Drug Target Discovery: A Special Focus on Infectious Diseases Tuberculosis, Malaria, Leishmaniasis, Trypanosomiasis and Gastritis, Infectious Disorders - Drug Targets 2013; 13 (5) . https://dx.doi.org/10.2174/1871526514666140321110312
DOI https://dx.doi.org/10.2174/1871526514666140321110312 |
Print ISSN 1871-5265 |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-3989 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Subject Index To Volume 7
Current Drug Targets A 30-years Review on Pharmacokinetics of Antibiotics: Is the Right Time for Pharmacogenetics?
Current Drug Metabolism Nano Particles: Emerging Warheads Against Bacterial Superbugs
Current Topics in Medicinal Chemistry Understanding Respiratory Syncytial Virus Infection to Improve Treatment and Immunity
Current Molecular Medicine Progress in Nanoparticulate Systems for Peptide, Proteins and Nucleic Acid Drug Delivery
Current Pharmaceutical Biotechnology Design and Synthesis of (<i>E</i>)-4-(2-Phenyl-2<i>H</i>-chromen-3-yl)but-3-en-2-ones and Evaluation of their <i>In Vitro</i> Antimicrobial Activity
Letters in Organic Chemistry Recent Advances on Isoniazide Derivatives
Anti-Infective Agents in Medicinal Chemistry Toll-Like Receptors and Kidney Diseases
Inflammation & Allergy - Drug Targets (Discontinued) Theoretical Modeling of HPV: QSAR and Novodesign with Fragment Approach
Current Computer-Aided Drug Design Correlation Between Clinical Manifestation and Radiological Findings In Pulmonary Tuberculosis-Human Immunodeficiency Virus Coinfection Patients In Sanglah Hospital, Bali, Indonesia
Current HIV Research Combating Malaria with Plant Molecules: A Brief Update
Current Medicinal Chemistry Co-medications and Drug-Drug Interactions in People Living with HIV in Turkey in the Era of Integrase Inhibitors
Current HIV Research Pharmacokinetics and Pharmacokinetic Variability of Heroin and its Metabolites: Review of the Literature
Current Clinical Pharmacology The Chemical Dynamics of NO and Reactive Nitrogen Oxides: A Practical Guide
Current Molecular Medicine Bacterial Zinc Proteases and their Inhibition
Current Enzyme Inhibition Can Mycobacterial Genomics Generate Novel Targets as Speed-Breakers Against the Race for Drug Resistance
Current Pharmaceutical Design Probiotics/Prebiotics in Viral Respiratory Infections: Implication for Emerging Pathogens
Recent Patents on Biotechnology New Approaches for Anti-Infective Drug Discovery: Antibiotics, Vaccines and Beyond
Current Drug Targets - Infectious Disorders Neglected Diseases - New Compounds and Treatments
Current Medicinal Chemistry Laboratory Techniques for Human Viral Encephalitis Diagnosis
Infectious Disorders - Drug Targets