Abstract
Nanoparticles mediated vaccine delivery is an emerging technology and considered as better adjuvant for delivering vaccines when compared to conventional delivery system. The purpose of this delivery system is to provide simple stable formulation that elicits lifelong immunity preferably with single shot. In line to develop the biodegradable polymer vaccine delivery system it is necessary to understand about the nature of polymer, type of antigen to be encapsulated, broad idea about immunological sketch. In this review, we attempt to provide an overview about the nano particle vaccine delivery system and interaction between nano particle and the immune system.
Keywords: Biodegradable polymers, immunological profile, nanoparticle, vaccine delivery.
Current Pharmaceutical Biotechnology
Title:Nanoparticles for Triggering and Regulation of Immune Response of Vaccines: Perspective and Prospective
Volume: 14 Issue: 15
Author(s): Sivakumar S. Moni, Mohammed M. Safhi and Bhakti B. Barik
Affiliation:
Keywords: Biodegradable polymers, immunological profile, nanoparticle, vaccine delivery.
Abstract: Nanoparticles mediated vaccine delivery is an emerging technology and considered as better adjuvant for delivering vaccines when compared to conventional delivery system. The purpose of this delivery system is to provide simple stable formulation that elicits lifelong immunity preferably with single shot. In line to develop the biodegradable polymer vaccine delivery system it is necessary to understand about the nature of polymer, type of antigen to be encapsulated, broad idea about immunological sketch. In this review, we attempt to provide an overview about the nano particle vaccine delivery system and interaction between nano particle and the immune system.
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Cite this article as:
Moni S. Sivakumar, Safhi M. Mohammed and Barik B. Bhakti, Nanoparticles for Triggering and Regulation of Immune Response of Vaccines: Perspective and Prospective, Current Pharmaceutical Biotechnology 2013; 14 (15) . https://dx.doi.org/10.2174/1389201015666140317120843
DOI https://dx.doi.org/10.2174/1389201015666140317120843 |
Print ISSN 1389-2010 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-4316 |
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