A Convenient Synthesis of 2-Imino-1,3-Thiazine-4-One Derivatives from the Reaction of Primary Amines and Phenyl Isothiocyanate in the Presence of Acryloyl Chloride

Author(s): Amin Zolali, Farough Nasiri, Sonia Omid-Niakan

Journal Name: Combinatorial Chemistry & High Throughput Screening
Accelerated Technologies for Biotechnology, Bioassays, Medicinal Chemistry and Natural Products Research

Volume 17 , Issue 7 , 2014

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An efficient, one-pot and three-component synthesis of biologically important heterocyclic compounds is described from the reaction of primary amines and phenyl isothiocyanate in the presence of acryloyl chloride at room temperature without the need to use any catalyst.

Keywords: 1, 3-Thiazine, dithiocarbamate, MCRs, multicomponent, one-pot.

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Article Details

Year: 2014
Published on: 16 July, 2014
Page: [610 - 613]
Pages: 4
DOI: 10.2174/1386207317666140313110334
Price: $65

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