Vitamin D deficiency, a worldwide epidemic has been vastly studied in the last years and was found associated
with different medical conditions varying from cancer to immune diseases. In this review article we have proposed that
vitamin D is highly correlated with two chronic respiratory diseases, Asthma and COPD using population based and
biological studies. The mechanism linking between these respiratory diseases involves numerous agents ranging from cell
signaling pathway to anti-inflammatory cytokines. In addition, the role of vitamin D supplementation seems promising
especially in the management of Asthma disease.
Keywords: Anti-inflammatory, asthma, chronic obstructive pulmonary disease, pathophysiology, side effects, vitamin D.
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