Sequential Comorbidity of Anxiety and Depression in Youth: Present Knowledge and Future Directions

Author(s): Jessica L. Schleider, Elizabeth D. Krause, Jane E. Gillham

Journal Name: Current Psychiatry Reviews
Continued as Current Psychiatry Research and Reviews

Volume 10 , Issue 1 , 2014


Research suggests that a history of childhood anxiety correlates with and predicts adolescent depression. The present review synthesizes current knowledge of relations between childhood anxiety and adolescent depression, focusing on the possibility that primary anxiety in childhood may cause secondary depression in adolescents. Across existing studies, evidence strongly supports childhood anxiety as a risk factor for adolescent depression, and long-term follow-up studies of cognitive-behavioral childhood anxiety treatments may suggest a causal anxiety-depression link. However, mechanisms underlying this relationship remain unexplored. Future directions include careful assessment of comorbidity between anxiety and depressive disorders, longitudinal evaluations of anxiety and depression following interventions for childhood anxiety, and investigations of mediators and moderators of the anxiety-depression link. Finally, mechanisms by which the treatment of childhood anxiety might prevent depression in adolescents are proposed.

Keywords: Adolescents, anxiety, children, comorbidity, depression, prevention, sequential comorbidity.

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Article Details

Year: 2014
Published on: 29 January, 2014
Page: [75 - 87]
Pages: 13
DOI: 10.2174/1573400509666131217010652

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