Tuberculosis is one of the leading causes of morbidity and mortality worldwide. Current
treatment has several challenges, such as multi-drug resistance, extensively drug-resistance and
HIV co-infection. Problems related to patients, treatment and health care system also contribute
negatively to this panel. This review summarizes the main obstacles causing in the treatment of
tuberculosis and discusses several strategies to improve the treatment.
Keywords: Drug interactions, extensively drug-resistance, HIV, multi-drug resistance, treatment
improvement, tuberculosis, tuberculosis treatment.
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