Title:Novel Approach for the Synthesis of Pyrrolo[2,1-c][1,4]Benzoxazines and Pyrrolo[1,2-a]Quinoxalines
VOLUME: 17 ISSUE: 2
Author(s):Tayebeh Sanaeishoar, Somayeh Adibi-Sedeh and Saghar Karimian
Affiliation:Chemistry Department, Science and Research Branch, Islamic Azad University, Khouzestan, Iran.
Keywords:o-aminophenols, o-phenylenediamine, p-toluene sulfonic acid, pyrrolo[1, 2-a]quinoxaline, pyrrolo[2, 1-c][1, 4]benzoxazine, β-
nitrostyrenes.
Abstract:An efficient synthesis of alkyl 4,5-dihydro-4-oxo-2-phenylpyrrolo[2,1-c][1,4]benzoxazine-3-carboxylates and
alkyl 4,5-dihydro-4-oxo-2-phenylpyrrolo[1,2-a]quinoxaline-3-carboxylates is described. This involves a three-component
reaction between o-aminophenols or o-phenylenediamine, acetylenic esters and β-nitrostyrene derivatives using p-toluene
sulfonic acid as a catalyst.
