Emergence of Functionalized Nanomedicines in Cancer Chemotherapy: Recent Advancements, Current Challenges and Toxicity Considerations

Author(s): Mahfoozur Rahman, Sarwar Beg, Aziz Ahmed, Suryakanta Swain

Journal Name: Recent Patents on Nanomedicine (Discontinued)

Volume 3 , Issue 2 , 2013

Abstract:

Past few decades have evidenced the extensive multidisciplinary investigation in the field of nanotechnology. Nanomedicines have emerged as promising carriers for delivery of diverse therapeutic molecules to the targeted sites. Owing to their unique physiochemical and optical properties, nanomedicines are used for multifunctional applications like delivery of therapeutic molecules, tumor targeting, imaging, etc. This present review mainly focuses on recent advancements, challenges and opportunities in the field of functionalized nanomedicines like liposomes, micelles, nanoparticles, and nanocomposites like nanotubes, graphenes and their derivatives for treatment of multiple types of cancers with special insight into the patent literatures. Also the nuances of the toxicological issues of the aforesaid nanosystems have been addressed.

Keywords: Chemotherapy, multifunctional nanocarriers, nanocomposites, nanomedicines, nanotoxicity.

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Article Details

VOLUME: 3
ISSUE: 2
Year: 2013
Page: [128 - 139]
Pages: 12
DOI: 10.2174/18779123113036660002
Price: $58

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