Solid Lipid Nanoparticles: An Innovative Nano-Vehicles for Drug Delivery

Author(s): Hema Chaudhary, Samita, Nitika Puri, Vikash Kumar

Journal Name: Nanoscience & Nanotechnology-Asia

Volume 4 , Issue 1 , 2014

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Nanotechnology is an emergent field with numerous applications in drug delivery, clinical medicine, nutriceuticals as well as in other fields also. In this techno, Solid lipid nanoparticles (SLN) is a part which consist solid colloidal particles ranging in size from 1 to 1000 nm and act as “magic bullet” when coupled with ligands/targeting ligands. SLN consisting of a solid-lipid promising advance delivery of lipophilic drugs and also used as an alternate for conventional carriers such as micro-emulsions, liposomes and nanoparticles based on natural/synthetic polymers. They are formulated from synthetic/natural lipids and optimize the drug delivery to provide a protection to sensitive drugs and obtain better/improve bioavailability with less toxicity (as compared to polymeric NPs) due to its biodegradable/bioacceptable nature. Moreover, Surface Modified SLNs is a new promising approach for protein loading and antigen delivery system.

Keywords: Nanotechnology, solid lipid nanoparticles (SLN), drug delivery, toxicity.

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Article Details

Year: 2014
Page: [38 - 44]
Pages: 7
DOI: 10.2174/22106812113036660003

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