We report herein the results of antifungal activity of fifteen 1,2,3-triazoles against Candida albicans, Candida
krusei, Candida parapsilosis, Candida kefyr, Candida tropicalis, Candida dubliniensis, Tricophyton rubrum, Microporum
canis and Aspergillus niger. All of the 1,2,3-triazoles were prepared from 1,3-dipolar cyclizations between aryl azides and
alkynes catalyzed by Cu(I), and several of the compounds exhibited antifungal activity with low cytotoxicity. The results
demonstrated the potential and importance of developing new 1,2,3-triazoles compounds with antifungal activity.