Abstract
Alkylboronate derivatives are important intermediates in organic synthesis and medicinal chemistry. The research of synthesizing alkylboronic acid derivatives has attracted great attention of chemists and many papers have reported various methods for preparing alkylboronates based on transition-metal-catalyzed hydroboration. In this review, we summarize the methods of synthesizing alkylboronate derivatives with different catalysts, such as Rhodium, Palladium, Copper, Iridium, Iron, Magnesiu, Platinum, Nickel and so on. Pinacolborane, bispinacolatodiboron and catecholborane are applied as important reagents and substrates with different skeleton structures and functional groups are employed to prepare diversity of alkylboronates.
Keywords: Alkylboronate, alkylboronic derivatives, catalyst, hydroboration, transition metal.
Current Organic Synthesis
Title:Alkylboronate Synthesis Based on Transition Metal-Catalyzed Hydroboration.
Volume: 10 Issue: 5
Author(s): Saipeng Huang, Yuanchao Xie, Shaolei Wu, Meirong Jia, Junhua Wang, Wenfeng Xu and Hao Fang
Affiliation:
Keywords: Alkylboronate, alkylboronic derivatives, catalyst, hydroboration, transition metal.
Abstract: Alkylboronate derivatives are important intermediates in organic synthesis and medicinal chemistry. The research of synthesizing alkylboronic acid derivatives has attracted great attention of chemists and many papers have reported various methods for preparing alkylboronates based on transition-metal-catalyzed hydroboration. In this review, we summarize the methods of synthesizing alkylboronate derivatives with different catalysts, such as Rhodium, Palladium, Copper, Iridium, Iron, Magnesiu, Platinum, Nickel and so on. Pinacolborane, bispinacolatodiboron and catecholborane are applied as important reagents and substrates with different skeleton structures and functional groups are employed to prepare diversity of alkylboronates.
Export Options
About this article
Cite this article as:
Huang Saipeng, Xie Yuanchao, Wu Shaolei, Jia Meirong, Wang Junhua, Xu Wenfeng and Fang Hao, Alkylboronate Synthesis Based on Transition Metal-Catalyzed Hydroboration., Current Organic Synthesis 2013; 10 (5) . https://dx.doi.org/10.2174/15701794113109990060
DOI https://dx.doi.org/10.2174/15701794113109990060 |
Print ISSN 1570-1794 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6271 |
Call for Papers in Thematic Issues
Exploring the Role of Chemical Graph Theory in Advancing Current Organic Synthesis
Organic synthesis is a fundamental discipline in chemistry, crucial for the creation of complex molecules with diverse applications in pharmaceuticals, materials science, and beyond. However, the process of designing efficient synthetic routes for target molecules remains challenging. Chemical graph theory, a branch of theoretical chemistry, offers powerful tools for understanding ...read more
Photoswitches for Molecular Recognition
This Special Issue would cover the hot topics on synthesis and chemical and photophysical characterization of new photoswitchable derivatives and their applications on molecular recognition of metabolites and biological active compounds, both in physiological medium and in living cells. Photoswitches are compounds that can change their conformation or properties in ...read more
Related Journals
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
HDAC Inhibitors as Novel Anti-Cancer Therapeutics
Recent Patents on Anti-Cancer Drug Discovery Small Molecules ATP-Competitive Inhibitors of FLT3: A Chemical Overview
Current Medicinal Chemistry The Use of Infliximab in Dermatology
Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry Cosignaling Molecules Around LIGHT-HVEM-BTLA: From Immune Activation to Therapeutic Targeting
Current Molecular Medicine MicroRNAs in Colorectal Neoplasia: From Pathobiology to Clinical Applications
Current Pharmaceutical Biotechnology Viral and Non-Viral Approaches for Transient Delivery of mRNA and Proteins
Current Gene Therapy Editorial [Hot Topic:Strategies for Molecular-Based Treatment of Hematological Malignancies (Guest Editor: Per Ole Iversen)]
Current Drug Targets MiRNAs in Human Cancers: The Diagnostic and Therapeutic Implications
Current Pharmaceutical Design ARC - Augmented Renal Clearance
Current Pharmaceutical Biotechnology Endothelial and Circulating Progenitor Cells in Hematological Diseases and Allogeneic Hematopoietic Stem Cell Transplantation
Current Medicinal Chemistry Molecular and Biochemical Pathways Encompassing Diabetes Mellitus and Dementia
CNS & Neurological Disorders - Drug Targets SRC: Regulation, Role in Human Carcinogenesis and Pharmacological Inhibitors
Current Pharmaceutical Design Nano Anti-Cancer Drugs: Pros and Cons and Future Perspectives
Current Cancer Drug Targets Recent Advances in Small Molecule Prodrugs for Cancer Therapy
Anti-Cancer Agents in Medicinal Chemistry The Nuclear Orphan Receptor NR4A1 and NR4A3 as Tumor Suppressors in Hematologic Neoplasms
Current Drug Targets Evaluating Intestinal Permeability by Measuring Plasma Endotoxin and Diamine Oxidase in Children with Acute Lymphoblastic Leukemia Treated with High-dose Methotrexate
Anti-Cancer Agents in Medicinal Chemistry Pharmacokinetics-Guided Dosing of 5-Fluorouracil for Precision Cancer Treatment: A Focus on Colorectal Carcinoma
Applied Clinical Research, Clinical Trials and Regulatory Affairs microRNA Biogenesis Pathway as a Therapeutic Target for Human Disease and Cancer
Current Pharmaceutical Design Current Concepts and Future Directions in Radioimmunotherapy
Current Drug Discovery Technologies Editorial [Hot Topic: Innovative Therapeutical Approaches for Hematological Malignancies Based on Molecular Targeted Therapies (Executive Editor: Giorgio Zauli) ]
Current Pharmaceutical Design