Synthesis and Biological Evaluation of Novel N-[(7-pyridin-4-yl-2, 3- dihydro-benzofuran-2-yl) Methyl]-(4-methyl-1, 2, 3-thiadiazole-5-yl) Formamide as a Potent Immunosuppressant Agent

Author(s): Chen Fan, Yubin Wang, Peng Lu, Xiaojian Xue, Jinxiong She

Journal Name: Letters in Drug Design & Discovery

Volume 11 , Issue 3 , 2014


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Abstract:

N-[(7-pyridin-4-yl-2, 3-dihydro-benzofuran-2-yl) methyl]-(4-methyl-1, 2, 3-thiadiazole-5-yl)-Formamide (1) was synthesized and its immunosuppressive activity was evaluated. The results showed it had highly immunosuppressive activity and can be studied as lead compound in the development of immunosuppressant agent.

Keywords: Formamide derivatives, Synthesis, Immunosuppressive bioactivity.

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Article Details

VOLUME: 11
ISSUE: 3
Year: 2014
Published on: 03 February, 2014
Page: [375 - 379]
Pages: 5
DOI: 10.2174/15701808113106660084
Price: $65

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