Our research group has published numerous papers over the last three years on the reaction of nitrile oxides and
azomethine ylide with unsaturated tricyclic N-substituted dicarboximides selected according to the importance of possible
biological activities. These reactions cover full range of mechanistic pathways and timings of bond-forming processes to
give five-membered ring closure by 1,3-dipolar cycloaddition.
Keywords: Azomethine ylide, biological active molecules, 1, 3-dipolar cycloaddition, hydrazones, isoxazolines, nitrile
oxides, tricyclic imides.
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