Graviola (Annona muricata), atemoya (A. squamosa x A. cherimola), ata (A. squamosa) and biribá (Rollinia
mucosa) lyophilized fruit pulps and atemoya seeds were extracted with methanol at 100 °C and 10.3 MPascal pressure
using an Accelerated Solvent Extractor (ASE) and analyzed by NMR to see if they have the known toxicophores (an α,β-unsaturated γ-lactone and substituted tetrahydrofuran ring) that are in the neurotoxins annonacin and squamocin. The
spectra of extracts from graviola, ata and biribá pulp and atemoya seeds showed the possible presence of relatively large
amounts of these toxicophores. There was much less in the extracts of atemoya pulp. Thus, NMR analysis can be used to
screen these fruits for the possible presence of the known toxicophores. Moreover, the methanol-soluble material in all
four fruits showed the presence of glycosides as the major components.
Keywords: Parkinson's, annona muricata, A. squamosa x A. cherimola, rollinia mucosa.
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