Carbohydrate arrays are used as high-throughput screening platforms to study the carbohydrate-mediated recognition
events for glycobiology. The polysaccharide arrays are easy to fabricate by non-covalently or covalently
immobilizing polysaccharides onto array surfaces because polysaccharides have hydrophobic interactions.
Oligosaccharides must be derived and covalently or non-covalently immobilized onto array surfaces to fabricate
oligosaccharide arrays because they have hydrophilic interactions. At the moment, carbohydrate arrays are mainly used to
study the carbohydrate-protein interactions and carbohydrate-binding lectins or antibodies, which are possible to be
applied to clinics and diagnoses. This review mainly summed up the new fabrication strategies of carbohydrate arrays and
their applications in recent four years.
Keywords: Carbohydrate arrays, carbohydrate-protein interactions, carbohydrate-binding lectins or antibodies, fabrication
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Published on: 16 December, 2013
Page: [288 - 295]