Small Molecule PET-Radiopharmaceuticals

Author(s): Philip H. Elsinga, Rudi A.J.O. Dierckx

Journal Name: Current Pharmaceutical Design

Volume 20 , Issue 14 , 2014

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This review describes several aspects required for the development of small molecule PET-tracers. Design and selection criteria are important to consider before starting to develop novel PET-tracers. Principles and latest trends in 11C and 18F-radiochemistry are summarized. In addition an update of some new developments in regulatory aspects is supplied.

Keywords: PET, small molecules, radiochemistry, preclinical evaluation, carbon-11, fluorine-18.

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Article Details

Year: 2014
Published on: 08 May, 2014
Page: [2268 - 2274]
Pages: 7
DOI: 10.2174/13816128113196660661
Price: $65

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