Small Molecule PET-Radiopharmaceuticals

Title:Small Molecule PET-Radiopharmaceuticals

VOLUME: 20 ISSUE: 14

Author(s):Philip H. Elsinga and Rudi A.J.O. Dierckx

Affiliation:University Medical Center Groningen, University of Groningen, the Netherlands and Ghent University, Belgium.

Keywords:PET, small molecules, radiochemistry, preclinical evaluation, carbon-11, fluorine-18.

Abstract:This review describes several aspects required for the development of small molecule PET-tracers. Design and selection criteria are important to consider before starting to develop novel PET-tracers. Principles and latest trends in ¹¹C and ¹⁸F-radiochemistry are summarized. In addition an update of some new developments in regulatory aspects is supplied.

Cite this article as:

Philip H. Elsinga and Rudi A.J.O. Dierckx, “Small Molecule PET-Radiopharmaceuticals”, Current Pharmaceutical Design (2014) 20: 2268. https://doi.org/10.2174/13816128113196660661

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