Title:Neurobiological Influences on Recovery from Traumatic Brain Injury: The Role of Genetic Polymorphisms
VOLUME: 20 ISSUE: 26
Author(s):Starla M. Weaver and Jaclyn N. Portelli
Affiliation:1199 Pleasant Valley Way, West Orange, NJ 07052.
Keywords:Traumatic Brain Injury, Polymorphisms, Genes.
Abstract:Recovery from traumatic brain injury (TBI) is variable despite similarities in the severity or mechanism of injury. The study of
genetic polymorphisms offers an avenue for explaining individual differences in recovery and outcome following TBI. The current paper
reviews the role that genetic polymorphisms may play in influencing recovery and quality of life following TBI. Investigating the role of
polymorphisms on recovery from TBI may contribute to a better understanding of individual variations in outcome and has the potential
to lead to earlier and more targeted interventions and rehabilitation based on a patient’s genetic makeup. By outlining what has been discovered
about the relationship between polymorphisms and TBI we hope to both inform the medical community about the potential for
polymorphisms to influence recovery following TBI and provide a roadmap to researchers about the gaps in research within this population.
