Effect of Radio Frequency Waves of Electromagnetic Field on the Tubulin

Author(s): Mousavi Taghi, Riazi Gholamhosein, Rezayi-Zarchi Saeed.

Journal Name: Recent Patents on Endocrine, Metabolic & Immune Drug Discovery (Under Re-organization)

Volume 7 , Issue 3 , 2013

Abstract:

Microtubules (MTs) are macromolecular structures consisting of tubulin heterodimers and present in almost every eukaryotic cell. MTs fulfill all conditions for generation of electromagnetic field and are electrically polar due to the electrical polarity of a tubulin heterodimer. The calculated static electric dipole moment of about 1000 Debye makes them capable of being aligned parallel to the applied electromagnetic field direction. In the present study, the tubulin heterodimers were extracted and purified from the rat brains. MTs were obtained by polymerization in vitro. Samples of microtubules were adsorbed in the absence and in the presence of electromagnetic fields with radio frequency of 900 Hz. Our results demonstrate the effect of electromagnetic field with 900 Hz frequency to change the structure of MTs. In this paper, a related patent was used that will help to better understand the studied subject.

Keywords: Electromagnetic field, microtubules, polymerization, radio frequency, rat brain, tubulin.

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Article Details

VOLUME: 7
ISSUE: 3
Year: 2013
Page: [252 - 256]
Pages: 5
DOI: 10.2174/18722148113079990007
Price: $58

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