Atomic Force Microscopy and Anodic Porous Allumina of Nucleic Acid Programmable Protein Arrays

Author(s): Claudio Nicolini, Tercio Bezerra Correia, Enrico Stura, Claudio Larosa, Rosanna Spera, Eugenia Pechkova

Journal Name: Recent Patents on Biotechnology

Volume 7 , Issue 2 , 2013

Become EABM
Become Reviewer
Call for Editor


The methodological aspects are here presented for the NAPPA (Nucleic Acid Programmable Protein Arrays) characterization by atomic force microscopy and anodic porous alumina. Anodic Porous Alumina represents also an advanced on chip laboratory for gene expression contained in an engineered plasmid vector. The results obtained with CdK2, CDKN1A, p53 and Jun test genes expressed on NAPPA and the future developments are discussed in terms of our pertinent and recent Patents and of their possibility to overcome some limitations of present fluorescence detection in probing protein-protein interaction in both basic sciences and clinical studies.

Keywords: Atomic force microscopy, anodic porous alumina, NAPPA.

promotion: free to download

Rights & PermissionsPrintExport Cite as

Article Details

Year: 2013
Published on: 31 July, 2013
Page: [112 - 121]
Pages: 10
DOI: 10.2174/18722083113079990003

Article Metrics

PDF: 19