Title:Diffuse Large B-Cell Lymphoma with Involvement of the Chest Wall
VOLUME: 9 ISSUE: 2
Author(s):William H. Porr, Jonathan L. Henderson and Michael J. Morris
Affiliation:Department of Medicine (MCHE-MD), Brooke Army Medical Center, 3551 Roger Brooke Drive, Fort Sam Houston, TX 78234-0709, USA.
Keywords:Chest wall mass, lymphoma, pleural effusion, pyothorax.
Abstract:The development of a solitary chest wall mass due to underlying malignant lymphoma is an uncommon clinical
presentation. Diffuse large B-cell lymphoma, a type of non-Hodgkin's lymphoma, can affect multiple organs including
the lungs and pleural space. In some instances, there may be preexisting inflammation such as a chronic pyothorax before
lymphoma arises in these locations. Diffuse large B-cell lymphoma may frequently disseminate to extranodal sites, but
involvement of the chest wall has been reported in nearly 100 cases. This report details an unusual presentation of diffuse
large B-cell lymphoma from an enlarging chest wall mass and an underlying lymphomatous pleural effusion.
