Antimicrobial peptides are distributed in all forms of life presenting activity against bacteria, fungi, viruses,
parasites and cancer. In spite of the tremendous potential of these molecules, very few of them have been successfully developed
into therapeutics. The major problems associated with this new class of antimicrobials are molecule stability, toxicity
in host cells and production cost. A novel strategy to overcome these obstacles is conjugation to nanomaterials. Magnetic
nanoparticles have been widely studied in biomedicine due to their physicochemical properties. The conjugation of
antimicrobial peptides to magnetic nanoparticles could combine the best properties of both, generating an improved antimicrobial
nanoparticle. Here we provide an overview and discuss the potential application of magnetic nanoparticles
conjugated to antimicrobial peptides in overcoming diseases.