Nowadays, peptide based disease prevention is an important topic in biomedical science, which may radically
change the traditional use of biomaterials and improve the life quality. Self-assembled nanostructured peptides have been
receiving extreme attention in the drug delivery field due their high biocompatibility levels, better loading capacity, extended
circulation and localization in required target site. This article focuses on the composition and synthesis of different
forms of self-assembled peptide nanostructures as nanotubes, nanofibers, nanoparticles, nanotapes and nanogels. The
most important properties for their self assembled mechanism and their biomedical applications are also discussed. Various
potential applications of nanostructures peptide could be developed designed for therapeutic agent’s delivery, biosensors,
anticancerous and antimicrobial activities.