This review aims to highlight the most significant recent developments on synthetic strategies involving consecutive, domino
and multicomponent reactions featuring a Michael addition-initiating step for the synthesis of polycyclic heterocycles from 1,3-
dicarbonyls. These original sequences constitute more efficient and eco-compatible alternatives to known synthetic approaches to heterocyclic
compounds allowing for an even faster and highly desirable generation of molecular diversity and complexity.
Keywords: Consecutive reactions, Domino reactions, Multicomponent reactions, Michael addition, Polycyclic heterocycles, 1, 3-Dicarbonyl
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