A Facile and Convenient Approach for the One-Pot Synthesis of Naphtho- 1,3-oxazine Derivatives

Author(s): Santosh V. Goswami, Sunil S. Wagh, Shrikant S. Pendalwar, Sudhakar R. Bhusare

Journal Name: Current Catalysis

Volume 2 , Issue 3 , 2013

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A protocol describes the synthesis of naphtha-1,3-oxaizine derivatives via one-pot multi-component reaction of α-naphthol, formaldehyde and various substituted anilines catalyzed by L-proline as an efficient catalyst. A method offers delightful advantages such as mild reaction conditions, environmentally benign, easy experimental workup and good to excellent yields.

Keywords: Naphthoxazine, α-Naphthol, Formaldehyde, Aniline, L-proline.

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Article Details

Year: 2013
Page: [244 - 248]
Pages: 5
DOI: 10.2174/22115447113029990012
Price: $25

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