Thyroid Cancer: A Clinical Overview and A Useful Laboratory Manual

Indexed in: Book Citation Index, Science Edition, EBSCO.

Thyroid nodules have a high prevalence in populations where iodine deficiency rates are high and in people older than 50 years. Considering that only 5-10% of thyroid nodules are of malignant nature, ...
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Thyroid Cancer of Parafollicular Origin: Medullary Carcinoma

Pp. 76-84 (9)

Maria G. Castagna

Abstract

Medullary thyroid carcinoma is a tumor of the parafollicular C cells which accounts approximately 3% of thyroid cancer. It may occur as sporadic form or hereditary cancer both alone or associated with syndromes. In this chapter, epidemiology, genetic, diagnosis and treatment of medullary thyroid cancer will be discussed.

Keywords:

Medullary thyroid cancer, MEN2A, MEN2B, RET point mutations.

Affiliation:

Section of Endocrinology & Metabolism, Department of Internal Medicine, Endocrinology & Metabolism and Biochemistry, University of Siena, Siena, Italy.