Abstract
The present paper reviews the techniques allowing to assess sympathetic activity in humans, highlighting their advantages and limitations. While plasma noradrenaline measurement represents a useful and widely used method to evaluate sympathetic neural function, new approaches, developed starting from the seventies, like direct recording of sympathetic nerve traffic and noradrenaline spillover. These approaches have largely supplanted the plasma noradrenaline approach due to the precise estimation of the behavior of regional sympathetic neural function. The paper in particular will focus the microneurographic technique, considered as the gold standard, and on the new clinical evidences obtained with this technique.
Keywords: Cardiovascular diseases, microneurography, noradrenaline spillover, plasma noradrenaline, power spectral analysis, sympathetic nervous system.
Current Clinical Pharmacology
Title:How to Assess Sympathetic Nervous System Activity in Clinical Practice
Volume: 8 Issue: 3
Author(s): Gino Seravalle, Kyriakos Dimitriadis, Raffaella Dell'Oro and Guido Grassi
Affiliation:
Keywords: Cardiovascular diseases, microneurography, noradrenaline spillover, plasma noradrenaline, power spectral analysis, sympathetic nervous system.
Abstract: The present paper reviews the techniques allowing to assess sympathetic activity in humans, highlighting their advantages and limitations. While plasma noradrenaline measurement represents a useful and widely used method to evaluate sympathetic neural function, new approaches, developed starting from the seventies, like direct recording of sympathetic nerve traffic and noradrenaline spillover. These approaches have largely supplanted the plasma noradrenaline approach due to the precise estimation of the behavior of regional sympathetic neural function. The paper in particular will focus the microneurographic technique, considered as the gold standard, and on the new clinical evidences obtained with this technique.
Export Options
About this article
Cite this article as:
Seravalle Gino, Dimitriadis Kyriakos, Dell'Oro Raffaella and Grassi Guido, How to Assess Sympathetic Nervous System Activity in Clinical Practice, Current Clinical Pharmacology 2013; 8 (3) . https://dx.doi.org/10.2174/1574884711308030003
DOI https://dx.doi.org/10.2174/1574884711308030003 |
Print ISSN 1574-8847 |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-3938 |
Related Articles
-
Microvascular Function/Dysfunction Downstream a Coronary Stenosis
Current Pharmaceutical Design The Use of Exercise Echocardiography in the Evaluation of Mitral Regurgitation
Current Cardiology Reviews Candidate Susceptibility Genes in Alzheimers Disease Are at High Risk for Being Forgotten - They Dont Give Peace of Mind...
Current Drug Metabolism Novel Inflammatory Indices in Aortic Disease
Current Medicinal Chemistry Targeting Tumorangiogenesis in Lung Cancer by Suppression of VEGF and its Receptor - Results from Clinical Trials and Novel Experimental Approaches
Current Medicinal Chemistry Red Wine, Arterial Stiffness and Central Hemodynamics
Current Pharmaceutical Design Cell-free Nucleic Acids as a Non-Invasive Route for Investigating Atherosclerosis
Current Pharmaceutical Design Improved Methods of Extraction and In Vitro Evaluation of Antimicrobial Potential of Stem Bark of Terminalia arjuna
Current Biochemical Engineering (Discontinued) Relation of Neck Circumference with Total Body Fat and BMI
Current Nutrition & Food Science Choice of Antihypertensive Treatment in Subjects with Pre-Diabetes. Is There a Dream After the Navigator
Current Vascular Pharmacology Development of Nitrendipine Nanoliposome for Transdermal Drug Delivery: Preparation, Characterization and Permeation Studies
Drug Delivery Letters Testosterone and Cardioprotection Against Myocardial Ischemia
Cardiovascular & Hematological Disorders-Drug Targets Teratological Consequences of Nitric Oxide Synthesis Inhibition
Current Pharmaceutical Design Effect of Environmental Conditions on the Expression Levels of a Recombinant 11S Amaranth Globulin in Escherichia coli
Recent Patents on Biotechnology Effects of Quercetin against Mycotoxin Induced Cytotoxicity: A Mini- Review
Current Nutrition & Food Science Meet Our Editors
Current Metabolomics Mechanisms of Vascular Calcification and Associated Diseases
Current Pharmaceutical Design Vascular Oxidative Stress: A Key Factor in the Development of Hypertension Associated with Ethanol Consumption
Current Hypertension Reviews A Systematic Approach to Hypertensive Urgencies and Emergencies
Current Hypertension Reviews Molecular Docking Study of a Series of Substituted Xanthone Derivatives as Novel COX-2 Inhibitors Targeting Prostaglandin Endoperoxide Synthase -2
Current Enzyme Inhibition