A Simple and Highly Efficient Procedure for One-Pot Synthesis of 2- Azetidinones Using 3,5-Dinitrobenzoyl Chloride

Author(s): Alireza Darvishi, Maaroof Zarei, Mohammad Reza Akhgara

Journal Name: Letters in Organic Chemistry

Volume 10 , Issue 9 , 2013

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One-pot synthesis of 2-azetidinones has efficiently been carried out in excellent yields by treatment of imines and substituted acetic acids with 3,5-dinitrobenzoyl chloride in the presence of triethylamine. The method is remarkably convenient and pure products were obtained by simple crystallization.

Keywords: β-Lactam, 2-Azetidinone, Staudinger reaction, 3, 5-Dinitrobenzoyl chloride, Ketene, Imine.

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Article Details

Year: 2013
Published on: 31 August, 2013
Page: [645 - 650]
Pages: 6
DOI: 10.2174/15701786113109990037

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