During past decades, significant advancement in the field of ultrasound assisted processes revealed that this
method is broadly applicable to a variety of research fields allied to organic synthesis. Emblematically, employing this
technique as key step, a great number of multicomponent reactions have been developed for the creation of an assortment
of heterocyclic compounds. In this review, we attempt to give an overview about the use of multicomponent reaction under
ultrasound irradiation for synthesis of various heterocyclic compounds.