Implementation of a Biocircuit Implants for Neurotransmitter Release During Neuro-Stimulation

Author(s): Suw Young Ly, Dal woong Choi

Journal Name: Current Neurovascular Research

Volume 10 , Issue 3 , 2013

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Neurotransmitter assay of epinephrine (EP) was sought using a modified carbon nanotube paste electrode (PE). Using optimum conditions, cyclic voltammetry (CV) and the square wave (SW) stripping voltammetric working ranges were attained to 10-100 mgL-1 (CV) and 20-140 ngL-1 (SW). The relative standard deviation of 0.0549 (n=15) was obtained at 20.0 mgL-1 EP constant. Here, the analytical detection limit (S/N) was reached with 4.60 ngL-1 (2.5×10-11 molL-1) EP. The hand-made electrode was implanted into the in-vivo brain core of the animals and was used in chronoamperometric neuro detection. The results obtained are applicable in neuro sensing, physiological control, and other neuroscience fields.

Keywords: Epinephrine, neuro sens, electrochemical, brain, in vivo, interface.

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Article Details

Year: 2013
Page: [238 - 246]
Pages: 9
DOI: 10.2174/15672026113109990017
Price: $65

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