Abstract
Numerous studies in humans, animal models and cell lines have suggested the potential benefits from the consumption of green tea polyphenols, including prevention of cancer and heart diseases. However these potential effects have been strongly limited by green tea catechins low bioavailability, which hinders the development of therapeutic applications. In this review formulations that are being proposed for delivery of green tea catechins are discussed. New delivery systems are presented as valid alternatives to overcome the limitations such as green tea catechins poor stability or intestinal absorption.
Keywords: Antioxidant, drug delivery, epigallocatechin-3-gallate, green tea polyphenols, catechins, EGCG.
Current Medicinal Chemistry
Title:Drug-Delivery Systems of Green Tea Catechins for Improved Stability and Bioavailability
Volume: 20 Issue: 37
Author(s): C. F. Rodrigues, K. Ascenção, F. A.M. Silva, B. Sarmento, M. B.P.P. Oliveira and J. C. Andrade
Affiliation:
Keywords: Antioxidant, drug delivery, epigallocatechin-3-gallate, green tea polyphenols, catechins, EGCG.
Abstract: Numerous studies in humans, animal models and cell lines have suggested the potential benefits from the consumption of green tea polyphenols, including prevention of cancer and heart diseases. However these potential effects have been strongly limited by green tea catechins low bioavailability, which hinders the development of therapeutic applications. In this review formulations that are being proposed for delivery of green tea catechins are discussed. New delivery systems are presented as valid alternatives to overcome the limitations such as green tea catechins poor stability or intestinal absorption.
Export Options
About this article
Cite this article as:
Rodrigues F. C., Ascenção K., Silva A.M. F., Sarmento B., Oliveira B.P.P. M. and Andrade C. J., Drug-Delivery Systems of Green Tea Catechins for Improved Stability and Bioavailability, Current Medicinal Chemistry 2013; 20 (37) . https://dx.doi.org/10.2174/09298673113209990158
DOI https://dx.doi.org/10.2174/09298673113209990158 |
Print ISSN 0929-8673 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-533X |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Diabetes Mellitus: Channeling Care through Cellular Discovery
Current Neurovascular Research Mechanisms of Medial Arterial Calcification in Diabetes
Current Pharmaceutical Design Material-Based Engineering Strategies for Cardiac Regeneration
Current Pharmaceutical Design Impact of Nutrients on the Functioning of Intestinal Goblet Cells: Health and Therapeutic Perspectives
Current Nutrition & Food Science Long-term Etanercept Therapy Favors Weight Gain and Ameliorates Cachexia in Rheumatoid Arthritis Patients: Roles of Gut Hormones and Leptin
Current Pharmaceutical Design Synthesis of New A-CD Estrogenic Compounds: D-Homo-analogs Lacking B-ring
Current Organic Chemistry Diagnostic Value of Postprandial Triglyceride Testing in Healthy Subjects:A Meta-Analysis
Current Vascular Pharmacology MicroRNAs in Cancer Therapy: From Bench to Bedside
Current Cancer Therapy Reviews Potential Role of TRP Channels in Cough Hypersensitivity?
Current Respiratory Medicine Reviews L-Dopa Related Hyperhomocysteinemia: A Possible Mediator of Toxicity?
Letters in Drug Design & Discovery Role of Polyphenols in Diet and Nutrition-An Updated Review
Current Nutrition & Food Science Active Phytochemicals from Chinese Herbs as Therapeutic Agents for the Heart
Cardiovascular & Hematological Agents in Medicinal Chemistry Inhibitory Effects of Some Bryophytes on Glutathione-S -Transferase
Current Enzyme Inhibition The Application of Rational Design on Phospholipase A2 Inhibitors
Current Medicinal Chemistry Recent Development on Anti-Obesity Compounds and their Mechanisms of Action: A Review
Current Medicinal Chemistry Dietary Fish Oil Reduces Colon Cancer Risk
Current Organic Chemistry Editorial (Thematic Issue: Disease Control and Active and Healthy Ageing: New Paradigms of Therapeutic Strategy)
Current Pharmaceutical Design Current Status and Ongoing Development of Reversing Agents for Novel Oral Anticoagulants (NOACs)
Recent Patents on Cardiovascular Drug Discovery Inhibition of Transcription Factors by Plant-Derived Compounds and their Implications in Inflammation and Cancer
Current Pharmaceutical Design Patent Ductus Arteriosus in the Preterm Infant: An Update on Morbidity and Mortality
Current Pediatric Reviews