Hydrogen sulfide (H2S), known for its unpleasant rotten egg smell and its high toxicity, has recently emerged
as an important mediator of human physiological and pathological processes, such as the regulation of cell growth, cardiovascular
protection, the stimulation of angiogenesis, gastric mucosal injury and Alzheimer’s disease. Due to its significant
actions in the physiology, H2S has attracted the abundant concern of numerous researchers in the cutting edge of
chemistry, biology and medicine. Recently, several fluorescent probes have been developed for detecting and elucidating
the role played by H2S in biological systems. This review highlights recent advances that have been made on the mechanism
and applications of fluorescent probes for the detection of H2S, demonstrating a new field in which remarkable improvements
have been accomplished over the last two years.