MicroRNAs (miRNAs) are an emerging class of highly conserved, non-coding small RNAs that regulate gene
expression on the post-transcriptional level by inhibiting the translation of protein from mRNA or by promoting the degradation
of mRNA. The involvement of miRNAs in the regulation of lipid metabolism, inflammatory response, cell cycle
progression and proliferation, oxidative stress, platelet activation, endothelial function, angiogenesis and plaque formation
and rapture indicates important roles in the initiation and progression of atherosclerosis. In the light of this evidence we
will review the role of miRNAs in atherosclerosis.