Background: Cognitive decline is common in Parkinson’s disease (PD) but may not be adequately identified by
the mini-mental state examination (MMSE), which is better suited to Alzheimer’s disease. The mini-mental Parkinson
(MMP) examination is a cognitive screening tool designed in French specifically for PD. We aimed to establish the validity
and reliability of the English language version of the MMP compared with the MMSE.
Methods: People with various stages of PD underwent testing with the MMP and MMSE, which was then compared with
a reference standard battery of neuropsychological tests to identify those with significant cognitive impairment.
Results: Forty-nine patients were recruited. Both the MMP and MMSE were significantly correlated with scores on all the
neuropsychological tests in the validation battery. The median MMP score was proportionally lower (80% of maximum)
than the MMSE (90% of maximum) in PD patients with cognitive impairment and those with prior neuropsychiatric complications
but there was no difference between the MMP and MMSE in areas under the curves (0.84) for detecting cognitive
impairment. Test-retest reliability of the MMP was good (intra-class correlation coefficient 0.793). An MMP of 28 or
lower out of 32 detected cognitive impairment with 87% sensitivity and 76% specificity.
Discussion: The English language version of the MMP has now been validated. It detects more cognitive deficits in PD
patients than the MMSE and identifies significant cognitive impairment in those with PD at least as well as the MMSE.