Vascular Contribution to Alzheimer Disease: Predictors of Rapid Progression

Author(s): Marina Diomedi, Giulia Misaggi

Journal Name: CNS & Neurological Disorders - Drug Targets
Formerly Current Drug Targets - CNS & Neurological Disorders

Volume 12 , Issue 4 , 2013


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Abstract:

Different courses of Alzheimer disease are observed in clinical practice. The rapidly progressive form could be associated with the presence of a major microcirculatory involvement and hemodynamic insufficiency. This short review aims to provide an overview of the current knowledge of cerebrovascular contribution to Alzheimer disease presentation and progression, hypothesizing the possible vascular markers of rapidly progressive form.

Keywords: Alzheimer disease, cerebral blood flow, disease progression, hemodynamics, risk factors, transcranial Doppler.

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Article Details

VOLUME: 12
ISSUE: 4
Year: 2013
Published on: 12 June, 2013
Page: [532 - 537]
Pages: 6
DOI: 10.2174/1871527311312040015
Price: $65

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