The synthesis of some novel (spirocycloalkenyl)trimethylsilylacetylenes employing the Sonogashira coupling
reaction of the corresponding novel spirocycloalkenyliodides with trimethylsilylacetylene and Pd(PPh3)2Cl2/CuI catalyst
in yields ranging 79-84% is reported. The compounds would serve as novel (spirocycloalkenyl)acetylenic anionic synthons.
Keywords: Acetylenic anionic synthons, enynes, silylacetylenes, spirocycloalkenes, Sonogashira coupling.
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Published on: 31 May, 2013
Page: [457 - 461]