Electrogenerated base induced dehydrocoupling of pyrazol-5-ones was investigated. The results showed that dehydrodimers
and dehydrotrimers were generated simultaneously under electrolytic conditions, and their ratio was mainly dependent on the reaction
temperature and the nature of the supporting electrolyte. It was observed that the formation of dimer 2 is preferred at lower temperatures
and that trimer 3 is preferentially formed at higher temperatures. In addition, higher yields of 3 could be obtained when NaI was used as
the supporting electrolyte. The dehydrocoupling reaction of pyrazol-5-ones to form dimer 2 and trimers 3 and 4 was proposed to be
through an EGB-induced cascade mechanism.
Keywords: Dehydrodimerization, dehydrotrimerization, electrogenerated bases, homocoupling, pyrazolone.
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